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DNA origami boosts sensitivity of rapid tests

9 Apr 2025

An LMU team has developed a technology that can amplify the signals of biomarkers in conventional test strips more than a hundredfold. Now the researchers are commercializing the method.

Since the Covid-19 pandemic, pretty much everybody is familiar with this technology: paper-based rapid test strips, also called lateral flow immunoassays (LFIAs). They enable easy detection of biomarkers that indicate the presence of specific pathogens or states of health. Now an LMU research group led by Heini Ijäs, Maximilian J. Urban, and Tim Liedl has managed to significantly improve such tests using a cutting-edge nanotechnology called DNA origami.

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